ALD01662

N-(4-(benzyloxy)-2-methylbutan-2-yl)-9H-fluoren-2-amine

• UNSPSC Code: 12352100
• PubChem Substance ID: 329772736
• NACRES: NA.22

Properties

• form: solid
• storage temp.: 2-8°C
• SMILES string: CC(CCOCC1=CC=CC=C1)(C)NC2=CC3=C(C=C2)C4=CC=CC=C4C3
• InChI: 1S/C25H27NO/c1-25(2,14-15-27-18-19-8-4-3-5-9-19)26-22-12-13-24-21(17-22)16-20-10-6-7-11-23(20)24/h3-13,17,26H,14-16,18H2,1-2H3
• InChI key: ZHIWNDDZLBTMEB-UHFFFAOYSA-N

Description

Application

Traditionally challenging to access, this hindered amine provides a chemically differentiated building block for organic synthesis and medicinal chemistry, specifically for preparation of drug candidates containing hindered amine motifs. Additionally, this and over 80 other sterically hindered secondary amines in the Sigma-Aldrich portfolio provide structurally distinct screening compounds. Screen several through Aldrich Market Select. This hindered amine was accessed via a recent publication reported by Baran and coworkers using an innovative hydroamination method.

Other Notes

Practical olefin hydroamination with nitroarenes

Product of KemXTree

Safety Information

• Hazard Statements: H413
• Hazard Classifications: Aquatic Chronic 4
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable