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712582

Sigma-Aldrich

O-[N-(3-Maleimidopropionyl)aminoethyl]-O′-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol

≥90% (NMR)

Synonym(s):

N-[15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamide, monodisperse Mal-PEG4-NHS-ester

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About This Item

Empirical Formula (Hill Notation):
C22H31N3O11
CAS Number:
756525-99-2
Molecular Weight:
513.50
MDL number:
MFCD11041113
UNSPSC Code:
12352200
PubChem Substance ID:
329763136
NACRES:
NA.22

Assay

≥90% (NMR)

form

liquid

reaction suitability

reagent type: cross-linking reagent

functional group

NHS ester
maleimide

storage temp.

−20°C

SMILES string

O=C(NCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)CCN2C(C=CC2=O)=O

InChI

1S/C22H31N3O11/c26-17(5-8-24-18(27)1-2-19(24)28)23-7-10-33-12-14-35-16-15-34-13-11-32-9-6-22(31)36-25-20(29)3-4-21(25)30/h1-2H,3-16H2,(H,23,26)

InChI key

XSRYGQJQNPJNKZ-UHFFFAOYSA-N

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG5439
BCCB8440
BCBT5995
BCBR8077V
BCBL9603V

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Articles

Polyethylene Glycol Building Blocks for PEGylation

Circulatory half-life is a key success factor for new drugs. In this respect, PEGylation or PEG-ing—the modification of potential candidates ranging from non-peptidic small molecules to peptides and proteins, antibody fragments, aptamers, and saccharides or oligonucleotides with polyethylene glycol chains—offers numerous advantages.

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