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701963

Sigma-Aldrich

Poly(ethylene glycol) diacrylate

average Mn 6,000, acrylate, ≤1,500 ppm MEHQ as inhibitor

Synonym(s):

Polyethylene glycol, PEG diacrylate

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About This Item

CAS Number:
26570-48-9
MDL number:
MFCD00081876
UNSPSC Code:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) diacrylate, average Mn 6,000, contains ≤1500 ppm MEHQ as inhibitor

form

solid

mol wt

average Mn 6,000

contains

≤1500 ppm MEHQ as inhibitor

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

transition temp

Tm 59-63 °C

Ω-end

acrylate

α-end

acrylate

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

−20°C

SMILES string

OCCO.OC(=O)C=C

InChI

1S/C8H10O4/c1-3-7(9)11-5-6-12-8(10)4-2/h3-4H,1-2,5-6H2

InChI key

KUDUQBURMYMBIJ-UHFFFAOYSA-N

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General description

Poly(ethylene glycol)diacrylate (PEGDA) is a long chain, hydrophilic and crosslinking monomer widelyused in tissue engineering.

Application

Patterning of PEG-based Hydrogels- Engineering Spatial Complexity
PEGDA is widely used as a scaffolding material for tissue engineering applications due to its biocompatibility and inherent resistance to protein adhesion.

It can be used as an alloying agent to prepare polymer membranes for gas separation applications. For example, an alloyed poly(Ether Block Amide)/ PEGDA membrane can be used for the separation of CO2/H2.

It can also be used as aprecursor to fabricate polymer electrolyte membranes(PEMs) for flexible Li-ionbatteries. The addition of PEGDA enhances the ionic conductivity, thermal stability,and mechanical toughness of PEMs.

Features and Benefits

  • Highly hydrophilic
  • Non-toxic
  • Biocompatible
  • Non-immunogenic

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H315,H317,H318

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shaun P Garland et al.
Langmuir : the ACS journal of surfaces and colloids, 30(8), 2101-2108 (2014-02-15)
A growing body of literature broadly documents that a wide array of fundamental cell behaviors are modulated by the physical attributes of the cellular microenvironment, yet in vitro assays are typically carried out using tissue culture plastic or glass substrates
Eyal Karzbrun et al.
Nature physics, 14(5), 515-522 (2018-05-16)
Human brain wrinkling has been implicated in neurodevelopmental disorders and yet its origins remain unknown. Polymer gel models suggest that wrinkling emerges spontaneously due to compression forces arising during differential swelling, but these ideas have not been tested in a
Adel Badria et al.
Journal of materials science. Materials in medicine, 29(11), 175-175 (2018-11-11)
Heart valve diseases remain common in industrialized countries. Bioprosthetic heart valves, introduced as free of anticoagulation therapy alternatives to mechanical substitutes. Still they suffer from long term failure due to calcification. Different treatment methods introduced to inhibit calcification, have so
Ruohong Shi et al.
Small (Weinheim an der Bergstrasse, Germany), 16(37), e2002946-e2002946 (2020-08-11)
Hydrogels with the ability to change shape in response to biochemical stimuli are important for biosensing, smart medicine, drug delivery, and soft robotics. Here, a family of multicomponent DNA polymerization motor gels with different polymer backbones is created, including acrylamide-co-bis-acrylamide

Articles

Patterning of PEG-based Hydrogels - Engineering Spatial Complexity

In this article, we will discuss the benefits and limitations of several 2D and 3D scaffold patterning techniques that can be applied in the presence of cells. Although these methods will be discussed in the context of poly(ethylene glycol) (PEG)-based hydrogels, they can technically be applied to any optically transparent, photoactive substrate.

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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