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457647

Sigma-Aldrich

Poly(D,L-lactide-co-caprolactone)

DL-lactide 86 mol %

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About This Item

MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

form

solid

feed ratio

lactide:caprolactone 85:15

composition

DL-lactide, 86 mol %

inherent viscosity

0.7-0.9 dL/g, in chloroform(lit.)

transition temp

Tg 16 °C

storage temp.

2-8°C

SMILES string

CC(O)C(O)=O.OCCCCC(O)=O

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Application

Poly(DL-lactide-co-caprolactone) (PLA-PCL) is a biodegradable block copolymer that may be used as monofilament sutures and nanoparticle-based drug delivery systems.

Features and Benefits

Biocompatible, biodegradable polymer.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Polymeric scaffolds in tissue engineering application: a review.
Dhandayuthapani B, et al.
International Journal of Polymer Science (2011)
Novel docetaxel-loaded nanoparticles based on poly (lactide-co-caprolactone) and poly (lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies.
Sanna V, et al.
Nanoscale Research Letters, 6(1), 260-260 (2011)

Articles

We will explore the technological advances that have contributed toward the progress of 3DP of tissue engineering scaffolds, current materials used to create 3DP scaffolds, and the challenges that remain.

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

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