201014
N-Benzylbenzamide
≥98%
Synonym(s):
Benzoic acid benzylamide, N-(Phenylmethyl)benzamide, N-Benzoylbenzylamine
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About This Item
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Quality Level
Assay
≥98%
mp
104-106 °C (lit.)
solubility
acetone: 25 mg/mL, clear, colorless
functional group
amide
phenyl
SMILES string
O=C(NCc1ccccc1)c2ccccc2
InChI
1S/C14H13NO/c16-14(13-9-5-2-6-10-13)15-11-12-7-3-1-4-8-12/h1-10H,11H2,(H,15,16)
InChI key
LKQUCICFTHBFAL-UHFFFAOYSA-N
General description
N-Benzylbenzamide inhibits the activity of tyrosinase.
Application
A convenient precursor to α-substituted benzylamines and an indicator for the titration of butyllithium and other lithium bases. For references see Aldrichimica Acta .
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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A series of potent inhibitors of tyrosinase and their structure-activity relationships are described. N-Benzylbenzamide derivatives (1-21) with hydroxyl(s) were synthesized and tested for their tyrosinase inhibitory activity. With this series, compound 15 provided a potent tyrosinase inhibition: it effectively inhibited
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