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Key Documents

201014

Sigma-Aldrich

N-Benzylbenzamide

≥98%

Synonym(s):

Benzoic acid benzylamide, N-(Phenylmethyl)benzamide, N-Benzoylbenzylamine

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About This Item

Linear Formula:
C6H5CONHCH2C6H5
CAS Number:
Molecular Weight:
211.26
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98%

mp

104-106 °C (lit.)

solubility

acetone: 25 mg/mL, clear, colorless

functional group

amide
phenyl

SMILES string

O=C(NCc1ccccc1)c2ccccc2

InChI

1S/C14H13NO/c16-14(13-9-5-2-6-10-13)15-11-12-7-3-1-4-8-12/h1-10H,11H2,(H,15,16)

InChI key

LKQUCICFTHBFAL-UHFFFAOYSA-N

General description

N-Benzylbenzamide inhibits the activity of tyrosinase.

Application

A convenient precursor to α-substituted benzylamines and an indicator for the titration of butyllithium and other lithium bases. For references see Aldrichimica Acta .

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Aldrichimica Acta, 11, 20-20 (1978)
Yae Eun Chong et al.
Biomedical chromatography : BMC, 33(11), e4653-e4653 (2019-07-20)
Ondansetron, a widely used antiemetic agent, is a P-glycoprotein (P-gp) substrate and therefore expression of P-gp at the blood-brain barrier limits its distribution to the central nervous system (CNS), which was observed to be reversed by coadministration with P-gp inhibitors.
Zsanett Dorkó et al.
Talanta, 162, 167-173 (2016-11-14)
A simple and efficient method is presented for assessing molecularly imprinted polymers (MIP) and other sorbents from the point of view of practical applications. The adsorption isotherms of the compounds, which need to be separated or detected in an application
Sung Jin Cho et al.
Bioorganic & medicinal chemistry letters, 16(10), 2682-2684 (2006-03-04)
A series of potent inhibitors of tyrosinase and their structure-activity relationships are described. N-Benzylbenzamide derivatives (1-21) with hydroxyl(s) were synthesized and tested for their tyrosinase inhibitory activity. With this series, compound 15 provided a potent tyrosinase inhibition: it effectively inhibited

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