143626

m-Tolyl isocyanate

99%

• Synonym(s): 3-Methylphenyl isocyanate
• Linear Formula: CH₃C₆H₄NCO
• CAS Number: 621-29-4
• Molecular Weight: 133.15
• Beilstein: 386149
• EC Number: 210-676-0
• MDL number: MFCD00002021
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848598
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: liquid
• refractive index: n20/D 1.5305 (lit.)
• bp: 75-76 °C/12 mmHg (lit.)
• density: 1.033 g/mL at 25 °C (lit.)
• functional group: isocyanate
• storage temp.: 2-8°C
• SMILES string: Cc1cccc(c1)N=C=O
• InChI: 1S/C8H7NO/c1-7-3-2-4-8(5-7)9-6-10/h2-5H,1H3
• InChI key: CPPGZWWUPFWALU-UHFFFAOYSA-N

Description

General description

m-Tolyl isocyanate undergoes polymerization reaction to form the corresponding polymers by using lanthanum isopropoxide as initiator.

Application

m-Tolyl isocyanate was used as reagent during the synthesis of C5-cyclohexyl analog of the cholecystokinin type-B receptor antagonist L-365,260.

Safety Information

• Pictograms: GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H314,H317,H330,H334,H335
• Precautionary Statements: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1C - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 2
• Flash Point(F): 149.0 °F - closed cup
• Flash Point(C): 65 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves