141038

2-Hydroxybenzonitrile

99%

• Synonym(s): 2-Cyanophenol, Salicylonitrile
• Linear Formula: NCC₆H₄OH
• CAS Number: 611-20-1
• Molecular Weight: 119.12
• Beilstein: 1210029
• EC Number: 210-259-3
• MDL number: MFCD00002145
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848487
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: powder
• bp: 149 °C/14 mmHg (lit.)
• mp: 92-95 °C (lit.)
• functional group: nitrile
• SMILES string: Oc1ccccc1C#N
• InChI: 1S/C7H5NO/c8-5-6-3-1-2-4-7(6)9/h1-4,9H
• InChI key: CHZCERSEMVWNHL-UHFFFAOYSA-N

Description

Application

2-Hydroxybenzonitrile may be used in the preparation of:

• methyl-(2-cyanophenoxy)acetate
• 3-amino-N-phenylbenzofuran-2-carboxamide
• 2-(2-oxo-2-phenylethoxy)benzonitrile
• 3-amino-2-cyanobenzo[b]furane

It may also be used as a directing group for meta-selective C-H bond alkenylation.

2-Hydroxybenzonitrile was used as starting reagent during the synthesis of:

• mono-alkoxyphenyloxazoline
• furanoside

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H317,H318
• Precautionary Statements: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1B
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves