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Merck

UHPLC/MS Analysis of Various Drug Substances on Titan C18

UHPLC/MS Analysis of Various Drug Substances on Titan C18 application for HPLC

Materiales

patrón

Referencia del producto
Descripción
Precios

Carbamazepine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Diazepam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Metoprolol tartrate solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Propranolol hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

CONDITIONS

column

Titan C18, 5 cm x 2.1 mm I.D., 1.9 μm particles (577122-U)

mobile phase

[A] 5 mM ammonium formate; [B] 5 mM ammonium formate in 90:10 (v:v) acetonitrile:water

gradient

30 to 70% B in 3.0 min

flow rate

0.3 mL/min

column temp.

35 °C

detector

MS/MS

injection

3 μL

sample

50 ng/mL in methanol

Descripción

Nota de análisis

A Titan C18 column provided rapid, baseline resolution of this set of drug substances. The highest quality LC-MS solvents were used to supply low background interference and low particulate contaminants for robust, trouble-free operation. Cerilliant CRMs provided reliable identification and quantification.

Información legal

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