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Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1.

Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1.

Organic & biomolecular chemistry (2009-03-06)

David Foley, Patrick Bailey, Myrtani Pieri, David Meredith

RESUMEN

Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro.

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Supelco

Nabumetone, analytical standard

Nabumetone, European Pharmacopoeia (EP) Reference Standard