V900422

Folic acid

Vetec^™, reagent grade, ≥97%

• Sinónimos: PteGlu, Pteroyl-L-glutamic acid, Vitamin M
• Fórmula empírica (notación de Hill): C₁₉H₁₉N₇O₆
• Número de CAS: 59-30-3
• Peso molecular: 441.40
• Beilstein: 100781
• Número CE: 200-419-0
• Número MDL: MFCD00079305
• Código UNSPSC: 12352106
• ID de la sustancia en PubChem: 329829830

Propiedades

• grado: reagent grade
• Línea del producto: Vetec^™
• Ensayo: ≥97%
• Formulario: powder
• técnicas: HPLC: suitable
• color: yellow to orange
• mp: >285 °C
• cadena SMILES: NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
• InChI: 1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
• Clave InChI: OVBPIULPVIDEAO-LBPRGKRZSA-N

Descripción

Descripción general

Folic acid belongs to vitamin B group and is also called as vitamin B₉ or folate. It is present as 5-methyltetrahydrofolate in humans. Grains, fruits and vegetables are dietary sources of folate. Pteroylmonoglutamate is a synthetic folate which comprises single glutamate and exists in the oxidized state.

Acciones bioquímicas o fisiológicas

Folic acid is essential for cell growth, brain functioning and plays a key role on serine production from glycine. It also coordinates with vitamin B₁₂ in maintaining iron levels. Deficiency of folate is implicated in megaloblastic anemia. Folic acid aids in the repair and synthesis of DNA. Dietary supplementation and fortification of folate in foods is recommended for pregnant women especially in the first trimester to avoid congenital malformation and neural tube defects (NTDs). However, folate fortification may also impose a moderate risk of developing prostate cancer. Supplementation of folate to colon cancer cells diminishes iron levels and impairs the cell division.

Información legal

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1