1604803

Ritonavir

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: 1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
• Fórmula empírica (notación de Hill): C₃₇H₄₈N₆O₅S₂
• Número de CAS: 155213-67-5
• Peso molecular: 720.94
• Número MDL: MFCD08694944
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• origen biológico: synthetic
• grado: pharmaceutical primary standard
• Agency: USP
• presión de vapor: <0.0000001 kPa ( 25 °C)
• familia API: ritonavir
• Formulario: powder
• envase: pkg of 200 mg
• fabricante / nombre comercial: USP
• condiciones de almacenamiento: protect from light
• color: white to tan
• solubilidad: acetonitrile: slightly soluble; ethanol: freely soluble; methanol: freely soluble; methylene chloride: freely soluble; water: practically insoluble
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• cadena SMILES: [s]1c(nc(c1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@@H](NC(=O)OCc4[s]cnc4)Cc3ccccc3)Cc2ccccc2)C(C)C
• InChI: 1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1
• Clave InChI: NCDNCNXCDXHOMX-XGKFQTDJSA-N

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.

Aplicación

Ritonavir USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Ritonavir Capsules
• Ritonavir Tablets
• Ritonavir Oral Solution
• Lopinavir and Ritonavir Tablets
• Lopinavir and Ritonavir Oral Solution

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302 + H312 + H332
• Consejos de prudencia: P261 - P280 - P301 + P312 + P330
• Clasificaciones de peligro: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable