1457607

Nateglinide

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: Fastic, N-[(trans-4-isopropylcyclohexyl)carbonyl]-D-phenylalanine, Starlix, Starsis
• Fórmula empírica (notación de Hill): C₁₉H₂₇NO₃
• Número de CAS: 105816-04-4
• Peso molecular: 317.42
• Número MDL: MFCD00875706
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329750535
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: nateglinide
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• cadena SMILES: CC(C)[C@@H]1CC[C@H](CC1)C(=O)N[C@H](Cc2ccccc2)C(O)=O
• InChI: 1S/C19H27NO3/c1-13(2)15-8-10-16(11-9-15)18(21)20-17(19(22)23)12-14-6-4-3-5-7-14/h3-7,13,15-17H,8-12H2,1-2H3,(H,20,21)(H,22,23)/t15-,16-,17-/m1/s1
• Clave InChI: OELFLUMRDSZNSF-BRWVUGGUSA-N
• Información sobre el gen: human ... ABCC8(6833) , KCNJ11(3767)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Acciones bioquímicas o fisiológicas

Nateglinide is a K_ir6.2/SUR1 channel inhibitor and antidiabetic.

Nateglinide is a Kir6.2/SUR1 channel inhibitor and antidiabetic. It is selective for the SUR1 subtype, which is found on pancreatic islet cells. Nateglinide evokes KATP channel-dependent insulin secretion (50-200 μM) in the absence and presence of insulin.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable