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Merck

1441301

USP

Metoprolol tartrate

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Lopressor

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About This Item

Fórmula lineal:
(C15H25NO3)2 · C4H6O6
Número de CAS:
Peso molecular:
684.81
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

metoprolol

fabricante / nombre comercial

USP

aplicaciones

pharmaceutical (small molecule)

formato

neat

cadena SMILES

O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2

InChI

1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1

Clave InChI

YGULWPYYGQCFMP-CEAXSRTFSA-N

Información sobre el gen

human ... ADRB1(153)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Metoprolol tartrate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Metoprolol Tartrate and Hydrochlorothiazide Tablets
  • Metoprolol Tartrate Compounded Oral Solution
  • Metoprolol Tartrate Compounded Oral Suspension
  • Metoprolol Tartrate Injection
  • Metoprolol Tartrate Tablets

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Pictogramas

Health hazardEnvironment

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Aquatic Chronic 2 - Repr. 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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C Narendra et al.
AAPS PharmSciTech, 7(2), E34-E34 (2006-06-27)
The purpose of the present study was to develop an optimized gastric floating drug delivery system (GFDDS) containing metoprolol tartrate (MT) as a model drug by the optimization technique. A 2(3) factorial design was employed in formulating the GFDDS with
Design and evaluation of mucoadhesive buccal drug delivery systems containing metoprolol tartrate.
Ramana, M. V., C. Nagda, and M. Himaja.
Indian Journal of Pharmaceutical Sciences, 69.4, 515-515 (2007)
Wenhuan Li et al.
Medicine, 93(28), e329-e329 (2014-12-20)
The sensitivity and specificity of 5 different image sets of dual-energy computed tomography (DECT) for the detection of first-pass myocardial perfusion defects have not systematically been compared using positron emission tomography (PET) as a reference standard. Forty-nine consecutive patients, with
I S Hamadeh et al.
Clinical pharmacology and therapeutics, 96(2), 175-181 (2014-03-19)
Metoprolol is a selective β-1 adrenergic receptor blocker that undergoes extensive metabolism by the polymorphic enzyme cytochrome P450 2D6 (CYP2D6). Our objective was to investigate the influence of CYP2D6 polymorphisms on the efficacy and tolerability of metoprolol tartrate. Two hundred
Rahil H Kassamali et al.
AJR. American journal of roentgenology, 203(4), 759-762 (2014-09-24)
The purpose of this study was to assess the safety of heart rate optimization by use of β-adrenergic blockade solely by the i.v. route before coronary CT angiography. The records of 679 patients undergoing CT coronary angiography after receiving i.v.

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