1133977

Cinacalcet hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: AMG 073 hydrochloride, KRN 1493 hydrochloride, N-[1-(R)-(-)-(1-naphthyl)ethyl]-3-[3(trifluoromethyl)phenyl]-1-aminopropane hydrochloride, NPS 1493 hydrochloride
• Fórmula empírica (notación de Hill): C₂₂H₂₂F₃N·HCl
• Número de CAS: 364782-34-3
• Peso molecular: 393.87
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: cinacalcet
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical (small molecule)
• formato: neat
• InChI: 1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m1./s1
• Clave InChI: QANQWUQOEJZMLL-PKLMIRHRSA-N

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Cinacalcet hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Acciones bioquímicas o fisiológicas

Cinacalcet is a positive allosteric modulator of the Calcium Sensing Receptor (CaSR) that acts as a calcimimetic. It increases the sensitivity of the calcium-sensing receptor to extracellular calcium resulting in a decrease in serum calcium levels.

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08,GHS05,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H302,H314,H317,H373,H413
• Consejos de prudencia: P260 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338 - P314
• Clasificaciones de peligro: Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1B - STOT RE 2
• Órganos de actuación: eye - retina
• Código de clase de almacenamiento: 8A - Combustible corrosive hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable