1019428

Amifostine thiol

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: WR-1065, 2-[(3-Aminopropyl)amino]ethanethiol dihydrochloride, WR-1065 dihydrochloride
• Fórmula empírica (notación de Hill): C₅H₁₄N₂S · 2HCl
• Número de CAS: 14653-77-1
• Peso molecular: 207.16
• Número MDL: MFCD00460339
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329748973
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: amifostine
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical (small molecule)
• formato: neat
• temp. de almacenamiento: −20°C
• cadena SMILES: Cl.Cl.NCCCNCCS
• InChI: 1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H
• Clave InChI: XDRLRDHLCIFZIW-UHFFFAOYSA-N

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Amifostine thiol USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Amifostine
• Amifostine for Injection

Acciones bioquímicas o fisiológicas

WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS05,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H302,H318
• Consejos de prudencia: P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
• Clasificaciones de peligro: Acute Tox. 4 Oral - Eye Dam. 1
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable