PHL86245

Pellitorine

phyproof^® Reference Substance

• Sinónimos: (2E,4E)-N-(2-Methylpropyl)-2,4-decadienamide, (2E,4E)-N-Isobutyl-2,4-decadienamide, 2E,4E-Decadienoic acid N-isobutylamide, trans-Pellitorin, trans-Pellitorine
• Fórmula empírica (notación de Hill): C₁₄H₂₅NO
• Número de CAS: 18836-52-7
• Peso molecular: 223.35
• Número MDL: MFCD01735995
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: primary reference standard
• Línea del producto: phyproof^® Reference Substance
• Ensayo: ≥90.0% (HPLC)
• fabricante / nombre comercial: PhytoLab
• Formato: neat
• temp. de almacenamiento: −20°C
• cadena SMILES: N(CC(C)C)C(=O)\C=C\C=C\CCCCC
• InChI: 1S/C14H25NO/c1-4-5-6-7-8-9-10-11-14(16)15-12-13(2)3/h8-11,13H,4-7,12H2,1-3H3,(H,15,16)/b9-8+,11-10+
• Clave InChI: MAGQQZHFHJDIRE-BNFZFUHLSA-N

Descripción

Descripción general

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Acciones bioquímicas o fisiológicas

ACAT inhibitor; α-Glucosidase inhibitor; anti-inflammatory;

Pellitorine is an α-Glucosidase inhibitor isolated from the roots of Piper Nigrum that exhibit anti-diabetic, anti-cancer, anti-bacterial and anti-inflammatory properties. Pellitorine is an ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor that inhibits cholesterol esterification in HepG2 cells. Also pellitorine exhibit potent larvicide activity in mosquito by Inhibition of gene expression encoding V-type H+-ATPase and aquaporine 4. Some new research suggests that anti-adipogenic activity of pellitorine depends on TRPV1.

Otras notas

This compound is commonly found in plants of the genus: achillea

Información legal

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable