567513-U
Discovery® HS F5 (5 µm) HPLC Columns
L × I.D. 5 cm × 4.6 mm, HPLC Column
Sinónimos:
Discovery Pentafluorophenyl PFP HPLC Column
About This Item
Productos recomendados
product name
Columna para HPLC Discovery® HS F5, 5 μm particle size, L × I.D. 5 cm × 4.6 mm
Materiales
stainless steel column
Agency
suitable for USP L43
Línea del producto
Discovery®
Características
endcapped
fabricante / nombre comercial
Discovery®
envase
1 ea of
Extensión del etiquetado
12% Carbon loading
Parámetros
≤70 °C temp. range
400 bar pressure (5801 psi)
técnicas
HPLC: suitable
LC/MS: suitable
L × D.I.
5 cm × 4.6 mm
superficie
300 m2/g
cobertura de la superficie
4 μmol/m2
impurezas
<10 ppm metals
matriz
silica gel, high purity, spherical particle platform
fully porous particle
grupo activo de la matriz
PFP (pentafluorophenyl) phase
tamaño de partícula
5 μm
tamaño de poro
120 Å
operating pH range
2-8
aplicaciones
food and beverages
técnica de separación
reversed phase
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Descripción general
• Selectividad única
• Retención similar a la C18 (algunas veces requiere una fase móvil más fuerte)
• Excelente forma del pico
• Estable, escaso sangrado en separaciones de CL/EM (LC/MS)
• Separaciones modulables de 3 a 10μm
Aplicación
- Optimization and validation of a bioanalytical HPLC-UV technique for simultaneous determination of underivatized phenylalanine and tyrosine in the blood for phenylketonuria diagnosis and monitoring.: This study utilizes the Discovery® HS F5 HPLC Column to develop an HPLC-UV method for the simultaneous determination of phenylalanine and tyrosine in blood, significantly advancing the diagnostic and monitoring capabilities for phenylketonuria (Rabti et al., 2024).
- A new RP-HPLC method as an auxiliary tool for optimization of sample preparation procedures for tracing of PPCPs of different hydrophilicities.: Demonstrates the application of the Discovery® HS F5 HPLC Column in optimizing sample preparation techniques for the detection of pharmaceuticals and personal care products in environmental samples, enhancing the analysis of diverse hydrophilic compounds (Portillo-Castillo et al., 2021).
- "Heart-cut" bidimensional achiral-chiral liquid chromatography applied to the evaluation of stereoselective metabolism, in vivo biological activity and brain response to chiral drug candidates targeting the central nervous system.: Utilizes the Discovery® HS F5 HPLC Column in a novel bidimensional chromatographic setup to study the stereoselective metabolism of CNS-targeting chiral drugs, contributing to a deeper understanding of their pharmacological profiles (Battisti et al., 2016).
- HPLC method development, validation, and impurity characterization of a potent antitumor indenoisoquinoline, LMP776 (NSC 725776).: This research employs the Discovery® HS F5 HPLC Column for developing an HPLC method to identify and characterize impurities in the antitumor drug LMP776, ensuring drug purity and compliance with regulatory standards (Wang et al., 2016).
- Development studies on determination of preservatives decomposition products.: Showcases the application of the Discovery® HS F5 HPLC Column in the analysis of decomposition products of preservatives, enhancing the safety assessments of food and pharmaceutical products (Zabrzewska et al., 2014).
Características y beneficios
- Unique selectivity
- Similar retention to C18 (sometimes requires stronger mobile phase)
- Excellent peak shape
- Stable, low-bleed LC-MS separations
- Scalable separations from 3 to 10μm particle sizes
Información legal
Aplicación
cartucho de precolumna
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