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Merck

40458

Supelco

1-Nitrosopiperidine solution

certified reference material, 5000 μg/mL in methanol

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About This Item

Número de CAS:
Código UNSPSC:
41116105

grado

certified reference material
TraceCERT®

Nivel de calidad

Línea del producto

TraceCERT®

CofA

current certificate can be downloaded

envase

ampule of 1 mL

concentración

5000 μg/mL in methanol

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

environmental

formato

single component solution

temp. de almacenamiento

2-8°C

InChI

1S/C5H10N2O/c8-6-7-4-2-1-3-5-7/h1-5H2

Clave InChI

UWSDONTXWQOZFN-UHFFFAOYSA-N

Aplicación

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Información legal

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes,Central nervous system

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

51.8 °F - closed cup

Punto de inflamabilidad (°C)

11 °C - closed cup


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Kinetics of the oxidation of N-aminopiperidine with chloramine
Darwich.Ch, et al.
Kinetics and Catalysis, 50, 103-110 (2009)
Hansen L Wong et al.
Chemical research in toxicology, 16(10), 1298-1305 (2003-10-21)
N-Nitrosopiperidine (NPIP) is a potent rat nasal carcinogen whereas N-nitrosopyrrolidine (NPYR), a hepatic carcinogen, is weakly carcinogenic in the nose. NPIP and NPYR may be causative agents in human cancer. P450-catalyzed alpha-hydroxylation is the key activation pathway by which these
Kinetics of the oxidation of N-aminopiperidine with chloramine
Darwich.Ch, et al.
Kinetics and Catalysis, 50(1), 103-110 (2009)
Xiao-Yuan Xie et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 88(4), 775-782 (2010-07-24)
The aim of this study was to explore the histogenesis and carcinogenesis of pulmonary cancer induced by N-nitrosopiperidine (NPIP) in mice. NPIP is a form of N-nitrosamine found in tobacco smoke, which has been shown to be a genotoxic chemical
I T Vermeer et al.
Mutation research, 428(1-2), 353-361 (1999-10-13)
Many constituents present in the human diet may inhibit endogenous formation of N-nitroso compounds (NOC). Studies with human volunteers showed inhibiting effects of intake of ascorbic acid and green tea consumption on nitrosation using the N-nitrosoproline test. The aim of

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