WH0005692M1

Monoclonal Anti-PSMB4 antibody produced in mouse

clone 6G7-E8, purified immunoglobulin, buffered aqueous solution

• Sinónimos: Anti-HN3, Anti-HsN3, Anti-PROS26, Anti-proteasome (prosome, macropain) subunit, beta type, 4
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 6G7-E8, monoclonal
• formulario: buffered aqueous solution
• reactividad de especies: human
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; indirect ELISA: suitable; western blot: 1-5 μg/mL
• isotipo: IgG1κ
• Nº de acceso GenBank: BC000331
• Nº de acceso UniProt: P28070
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... PSMB4(5692)

Descripción

Descripción general

Proteasome subunit β 4 (PSMB4), also referred to as 20S proteasome subunit β-7, is a non-catalytic β subunit of the 20S proteasome. It is composed of 233 amino acids and the gene encoding it is localized on human chromosome 1q21.3.

Inmunógeno

PSMB4 (AAH00331, 1 a.a. ~ 264 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MEAFLGSRSGLWAGGPAPGQFYRIPSTPDSFMDPASALYRGPITRTQNPMVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQTATVTEKGVEIEGPLSTETNWDIAHMISGFE

Acciones bioquímicas o fisiológicas

Proteasome subunit β 4 (PSMB4) associates with senescence evasion factor (SNEV), various signaling factors, viral proteins and lipopolysaccharides. It modulates the assembly of the proteasome and may be involved in proteasome signal regulation. PSMB4 has a role in the progression of epithelial ovarian cancer and many other types of cancers.

Forma física

Solution in phosphate buffered saline, pH 7.4

Información legal

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Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)