V9014

Anti-VMAT2 antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-SLC18A2, Anti-SVAT, Anti-SVMT, Anti-Solute carrier family 18 (vesicular monoamine), member 2, Anti-VAT2, Anti-VMAT2
• Número MDL: MFCD02097601
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• reactividad de especies: mouse, rat, human
• concentración: ~1 mg/mL
• técnicas: immunohistochemistry: 1:100-1:250; western blot: 1:500-1:1,000
• Nº de acceso UniProt: Q05940
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... SLC18A2(6571) ; mouse ... Slc18a2(214084) ; rat ... Slc18a2(25549)

Descripción

Descripción general

Vesicular monoamine transporter 2 (VMAT2) , also known as solute carrier family 18 member A2 (SLC18A2), is a transmembrane protein that acts at nerve terminals. It is expressed in platelets and in central, peripheral and enteric neurons. The gene encoding VMAT2 consists of 16 exons and is mapped to human chromosome 10q25.

Inmunógeno

synthetic peptide corresponding an internal sequence of human VMAT2. This sequence is identical in mouse and rat.

Aplicación

Anti-VMAT2 antibody produced in rabbit has also been used in immunofluorescence.

Anti-VMAT2 antibody produced in rabbit has been used in western blot analysis.

Acciones bioquímicas o fisiológicas

Vesicular monoamine transporter 2 (VMAT2) modulates the release of neurotransmitters like dopamine, serotonin and γ-amino butyric acid. It has a role in the accumulation of neurotransmitters in synaptic vesicles to prevent toxicity. VMAT2 has been linked to tardive dyskinesia and may be associated with Parkinson′s disease.

Forma física

solution in phosphate buffered saline, containing 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)