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U4754

Sigma-Aldrich

Anti-Lectin, Ulex europaeus-I antibody produced in rabbit

whole antiserum, delipidized

Sinónimos:

Anti-Gorse or Furze Lectin, Anti-UEA-I

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.46

origen biológico

rabbit

conjugado

unconjugated

forma del anticuerpo

whole antiserum

tipo de anticuerpo

primary antibodies

clon

polyclonal

Formulario

liquid

contiene

15 mM sodium azide

reactividad de especies

Ulex europaeus

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunohistochemistry (frozen sections): suitable
indirect immunofluorescence: 1:500 using human tissue

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Descripción general

The antibody may be used for studies of the vascular structures. It reacts specifically with UEA-I bound to human endothelial cells of normal and neoplastic blood and lymphatic vessels. Its uniform reaction with vessels enables differentation between vessels and artificial slits in the tissue.

Inmunógeno

Ulex europaeus from gorse seeds..

Aplicación

Anti-Lectin, Ulex europaeus-I antibody produced in rabbit has been used in double immunostaining of muscle capillary sections.

Acciones bioquímicas o fisiológicas

Lectin isolated from Ulex europaeus I is specific for α-L-fucose-containing glycocompounds. Due to this specificity it serves as a marker for vascular endothelial cells and tumors derived from them.

Descripción de destino

Lectins are highly specific carbohydrate binding proteins useful in carbohydrate and cell membrane studies, as well as cell agglutination and typing techniques.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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H Holthöfer et al.
Laboratory investigation; a journal of technical methods and pathology, 47(1), 60-66 (1982-07-01)
Ulex europaeus I agglutinin, a lectin specific for some alpha-L-fucose-containing glycocompounds, was used in fluorescence microscopy to stain cryostat sections of human tissues. The endothelium of vessels of all sizes was stained ubiquitously in all tissues studied as judged by
Alpine Skiing With total knee Arthro Plasty (ASWAP): metabolism, inflammation, and skeletal muscle fiber characteristics
Kristensen M, et al.
Scandinavian Journal of Medicine & Science in Sports, 25, 40-48 (2015)
Faïza Maloum et al.
American journal of physiology. Gastrointestinal and liver physiology, 300(6), G1065-G1079 (2011-03-19)
Bone morphogenetic protein (BMP) signaling within the gastrointestinal tract is complex. BMP ligands and their receptors are expressed in both epithelial and mesenchymal compartments, suggesting bidirectional signaling between these two entities. Despite an increasing interest in BMP signaling in gut
M Miettinen et al.
American journal of clinical pathology, 79(1), 32-36 (1983-01-01)
Some skin and soft tumors, which generally are assumed to be derived from endothelial cells or blood vessels, were characterized with fluorochrome-labeled Ulex europaeus I agglutinin (UEA I), recently shown to bind specifically to endothelial cells in various normal human
J M Sweeter et al.
Scientific reports, 11(1), 13037-13037 (2021-06-24)
Exacerbations of muco-obstructive airway diseases such as COPD and asthma are associated with epithelial changes termed mucous metaplasia (MM). Many molecular pathways triggering MM have been identified; however, the factors that regulate resolution are less well understood. We hypothesized that

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