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T3955

Sigma-Aldrich

TNP

≥95% (HPLC)

Sinónimos:

N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

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About This Item

Fórmula empírica (notación de Hill):
C20H16F3N7O2
Número de CAS:
519178-28-0
Peso molecular:
443.38
Número MDL:
MFCD16875436
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
329826781
NACRES:
NA.77

Nivel de calidad

100

Análisis

≥95% (HPLC)

formulario

powder

condiciones de almacenamiento

protect from light

color

yellow

solubilidad

DMSO: ≥10 mg/mL

emisor

Novartis

temp. de almacenamiento

2-8°C

cadena SMILES

[O-][N+](=O)c1ccc(CNc2nc(NCc3cccc(c3)C(F)(F)F)nc4[nH]cnc24)cc1

InChI

1S/C20H16F3N7O2/c21-20(22,23)14-3-1-2-13(8-14)10-25-19-28-17(16-18(29-19)27-11-26-16)24-9-12-4-6-15(7-5-12)30(31)32/h1-8,11H,9-10H2,(H3,24,25,26,27,28,29)

Clave InChI

DDSBPUYZPWNNGH-UHFFFAOYSA-N

Acciones bioquímicas o fisiológicas

TNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates.

Características y beneficios

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Nota de preparación

TNP is soluble in DMSO at a concentration that is greater than or equal to 10 mg/ml.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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