T1428
apo-Transferrin bovine
BioReagent, suitable for cell culture, ≥98%
Sinónimos:
Human serotransferrin
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About This Item
Productos recomendados
origen biológico
bovine
Nivel de calidad
Línea del producto
BioReagent
Ensayo
≥98%
Formulario
powder
técnicas
cell culture | mammalian: suitable
impurezas
iron, essentially free
solubilidad
H2O: 10 mg/mL
Nº de acceso UniProt
temp. de almacenamiento
2-8°C
Información sobre el gen
bovine ... TF(280705)
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Descripción general
apo-Transferrin is an iron-free form of transferrin that is present in circulation.
Aplicación
All cells require iron for the proper uptake of oxygen from their environment. Transferrin, a protein isolated from serum, causes the uptake and transport of iron from culture medium to the cells. This allows proper oxygen uptake and also stimulates growth-related enzyme activity. Iron-saturated transferrin (holo transferrin) is continually recycled after releasing iron and becomes iron-deficient transferrin (apo-transferrin). Choosing which form to use depends upon the culture conditions. In media such as Dulbecco′s Modified Eagle′s Medium/Ham′s Nutrient Mixture F12 (DMEM/F12) that contain high levels of iron salt, using apo-transferrin is preferred.
apo-Transferrin bovine has been used as a component of:
- basal medium for culturing bovine mammary epithelial cells
- minimum essential medium α (MEM-α) for spermatogonial stem cells (SSCs) culture
- induction medium for mesenchymal stem cell culture
Acciones bioquímicas o fisiológicas
apo-Transferrin (apoTf) aids in preventing iron accumulation in tissues, especially in non-transfusion dependent β-thalassemia.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Zeitschrift fur Naturforschung. C, Journal of biosciences, 63(1-2), 154-156 (2008-04-05)
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