Saltar al contenido
Merck
Todas las fotos(5)

Documentos clave

T1428

Sigma-Aldrich

apo-Transferrin bovine

BioReagent, suitable for cell culture, ≥98%

Sinónimos:

Human serotransferrin

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Número de CAS:
Número CE:
Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.83

origen biológico

bovine

Nivel de calidad

Línea del producto

BioReagent

Ensayo

≥98%

Formulario

powder

técnicas

cell culture | mammalian: suitable

impurezas

iron, essentially free

solubilidad

H2O: 10 mg/mL

Nº de acceso UniProt

temp. de almacenamiento

2-8°C

Información sobre el gen

bovine ... TF(280705)

¿Está buscando productos similares? Visita Guía de comparación de productos

Descripción general

apo-Transferrin is an iron-free form of transferrin that is present in circulation.

Aplicación

All cells require iron for the proper uptake of oxygen from their environment. Transferrin, a protein isolated from serum, causes the uptake and transport of iron from culture medium to the cells. This allows proper oxygen uptake and also stimulates growth-related enzyme activity. Iron-saturated transferrin (holo transferrin) is continually recycled after releasing iron and becomes iron-deficient transferrin (apo-transferrin). Choosing which form to use depends upon the culture conditions. In media such as Dulbecco′s Modified Eagle′s Medium/Ham′s Nutrient Mixture F12 (DMEM/F12) that contain high levels of iron salt, using apo-transferrin is preferred.
apo-Transferrin bovine has been used as a component of:
  • basal medium for culturing bovine mammary epithelial cells
  • minimum essential medium α (MEM-α) for spermatogonial stem cells (SSCs) culture
  • induction medium for mesenchymal stem cell culture

Acciones bioquímicas o fisiológicas

apo-Transferrin (apoTf) aids in preventing iron accumulation in tissues, especially in non-transfusion dependent β-thalassemia.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Monique P Gelderman et al.
Haematologica, 100(5), 611-622 (2015-01-27)
Intermediate beta-thalassemia has a broad spectrum of sequelae and affected subjects may require occasional blood transfusions over their lifetime to correct anemia. Iron overload in intermediate beta-thalassemia results from a paradoxical intestinal absorption, iron release from macrophages and hepatocytes, and
Keita Abe et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 63(1-2), 154-156 (2008-04-05)
We have investigated the mechanism of manganese ion uptake by apo-transferrin using a capillary electrophoresis method, and obtained clear evidence that oxidation state +3 and the binuclear unit of a manganese chelate are essential factors for the facile uptake by
Jia Wang et al.
Stem cell research & therapy, 10(1), 227-227 (2019-07-31)
High temperature has a very adverse effect on mammalian spermatogenesis and eventually leads to sub- or infertility through either apoptosis or DNA damage. However, the direct effects of heat stress on the development of spermatogonial stem cells (SSCs) are still
Shanshan Li et al.
Journal of animal science and biotechnology, 7, 44-44 (2016-08-06)
The objective of this study was to study how changing the ratio of Lys to Thr, Lys to His, and Lys to Val affects the expression of lipogenic genes and microRNA (miRNA) in bovine mammary epithelial cells. Triplicate cultures with
Luca De Toni et al.
Frontiers in endocrinology, 13, 915096-915096 (2022-07-12)
Per- and poly-fluorinated alkyl substances (PFAS) are environment-persitent emerging endocrine disrupting chemicals raising health concerns worldwide. Exposure to PFAS has been associated with the imbalance of thyroid hormones. However, available studies addressing the cell mechanism underlying thyroid disrupting feature of

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico