SRP8037

IL-36γ mouse

>95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized

• Sinónimos: Interleukin-1 family member 9, Interleukin-36γ, SSI-3
• Código UNSPSC: 12352202
• NACRES: NA.32

Propiedades

• Nombre del producto: IL-36γ mouse, recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)
• origen biológico: mouse
• recombinante: expressed in E. coli
• conjugado: untagged
• Ensayo: >95% (SDS-PAGE)
• Formulario: lyophilized
• mol peso: ~17 kDa
• envase: pkg of 10 μg
• impurezas: <0.01 EU/μg endotoxin, tested
• color: white
• Nº de acceso UniProt: Q8R460
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: mouse ... Il36g(215257)

Descripción

Descripción general

IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

Forma física

Lyophilized from PBS and 0.5% trehalose.

Reconstitución

Reconstitute with 100 μL deionized water.

Otras notas

IL-36gamma (mouse) (aa 13-164) is untagged.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable