SRP6159
FGF-basic human
recombinant, expressed in human cells, ≥95% (SDS-PAGE)
Sinónimos:
FGF-2, FGF-b, HBGF-2, HBGH-2, Prostatropin
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Productos recomendados
origen biológico
human
recombinante
expressed in human cells
Análisis
≥95% (SDS-PAGE)
formulario
lyophilized
mol peso
17 kDa (monomer, non-glycosylated)
envase
pkg of 10 μg
técnicas
cell culture | mammalian: suitable
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
dry ice
temp. de almacenamiento
−70°C
Información sobre el gen
human ... FGF2(2247)
Descripción general
FGF-basic is a member of the fibroblast growth factor (FGF) family. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. The gene encoding this protein is localized on human chromosome 4q28.
Acciones bioquímicas o fisiológicas
FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. The protein associates with fibroblast growth factor receptors 1, 2 and 3 (FGFR-1, -2, -3).
Forma física
Lyophilized from a PBS solution.
Nota de preparación
Centrifuge the vial prior to opening.
Reconstitución
Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Los clientes también vieron
Cigdem Usul Afsar et al.
International journal of clinical and experimental pathology, 8(9), 9760-9771 (2015-12-01)
Non-small cell lung carcinoma is the leading cause of cancer related to death in the world. Squamous cell lung carcinoma (SqCLC) is the second most frequent histological subtype of lung carcinomas. Recently, growth factors, growth factor receptors, and signal transduction
Yuriko Katoh et al.
International journal of molecular medicine, 17(3), 529-532 (2006-02-09)
WNT, FGF and Hedgehog signaling pathways network together during embryogenesis, tissue regeneration, and carcinogenesis. FGF16, FGF18, and FGF20 genes are targets of WNT-mediated TCF/LEF-beta-catenin-BCL9/BCL9L-PYGO transcriptional complex. SPROUTY (SPRY) and SPRED family genes encode inhibitors for receptor tyrosine kinase signaling cascades
Mingming Hu et al.
PloS one, 11(1), e0147374-e0147374 (2016-01-30)
Basic fibroblast growth factor (bFGF) is known to stimulate angiogenesis and thus to influence the proliferation, migration and survival of tumor cells. Many studies examined the relationship between human bFGF overexpression and survival in lung cancer patients, but the results
Arsenii Zabirnyk et al.
Frontiers in pharmacology, 11, 568764-568764 (2021-01-05)
Background: No pharmacological treatment exists to prevent or stop the calcification process of aortic valves causing aortic stenosis. The aim of this study was to develop a robust model of induced calcification in whole aortic valve leaflets which could be
Abha Sahni et al.
Blood, 104(12), 3635-3641 (2004-08-07)
We have shown previously that fibrin(ogen) binding potentiates the capacity of fibroblast growth factor 2 (FGF-2) to stimulate endothelial cell (EC) proliferation. We have now investigated the receptor requirement for EC proliferation by fibrinogen-bound FGF-2. ECs were cultured with 25
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico