SRP4908

Visfatin

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

• Sinónimos: Nicotinamide phosphoribosyltransferase, Pre-B-cell colony-enhancing factor 1 homolog
• Código UNSPSC: 12352200

Propiedades

• origen biológico: mouse
• recombinante: expressed in E. coli
• Ensayo: ≥95% (HPLC); ≥95% (SDS-PAGE)
• Formulario: lyophilized
• mol peso: ~55.0 kDa
• envase: pkg of 10 μg
• condiciones de almacenamiento: avoid repeated freeze/thaw cycles
• impurezas: endotoxin, tested
• Nº de acceso NCBI: Q99KQ4
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: mouse ... Nampt(59027)

Descripción

Descripción general

Visfatin is also called pre-B cell colony enhancing factor, nicotinamide phosphoribosyltransferase, pre-B-cell colony-enhancing factor 1 homolog, NAmPRTase, Nampt and PBEF. Visfatin is an adipocytokine produced by visceral fat.

Acciones bioquímicas o fisiológicas

Visfatin has a role in mammalian nicotinamide adenine dinucleotide (NAD⁺) biosynthesis. Studies have shown that mice deficient in visfatin in the forebrain excitatory neurons show hyperactivity, diminished anxiety-like behaviors and impaired learning and memory. It has also been shown that visfatin stimulates glucose uptake and adenosine monophosphate-activated protein kinase (AMPK) phosphorylation in mouse C2C12 skeletal muscle cells.

Forma física

Lyophilized without any additives.

Reconstitución

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in PBS to the concentration of 0.1-1 mg/mL.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable