SRP0700

STAT5B Protein

recombinant

• Código UNSPSC: 12352202
• NACRES: NA.77

Propiedades

• recombinante: expressed in baculovirus infected Sf9 cells
• Análisis: 70-90% (SDS-PAGE)
• formulario: frozen liquid
• mol peso: ~115 kDa
• concentración: 0.2 μg/μL
• nº de acceso: BC065227
• Condiciones de envío: dry ice
• temp. de almacenamiento: −70°C
• Información sobre el gen: human ... STAT5B(6777)

Descripción

Aplicación

Useful for Western blot.

Acciones bioquímicas o fisiológicas

Recombinant full-length human STAT5B was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. STAT5B or signal transducer and activator of transcription 5B is a member of the STAT family of transcription factors. STATs are phosphorylated by the receptor associated kinases and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B is activated in response to a variety of cytokines ⁽¹⁾. The JAK/STAT pathway mediates a key signal from the somatic gonad that regulates male germline sexual development ⁽²⁾. STAT5B is critical for maintenance of tolerance in vivo and it is proposed that STAT5B is probably activated by IL2R.

Reconstitución

Formulated in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

Almacenamiento y estabilidad

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable