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Documentos clave

SRP0352

Sigma-Aldrich

TRKC active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)

Sinónimos:

NT-3 Receptor, NTKR3, Neurotrophic Tyrosine Kinase Receptor, type 3

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About This Item

Número de CAS:
2122170-03-8
Código UNSPSC:
12352200
NACRES:
NA.32

origen biológico

human

recombinante

expressed in baculovirus infected Sf9 cells

Análisis

≥70% (SDS-PAGE)

formulario

aqueous solution

mol peso

68 kDa

envase

pkg of 10 μg

técnicas

activity assay: suitable
inhibition assay: suitable

Nº de acceso NCBI

NM_002530

Nº de acceso UniProt

Q16288

Condiciones de envío

dry ice

temp. de almacenamiento

−70°C

Información sobre el gen

human ... NTRK3(4916)

Descripción general

Human TRKC, also known as NTKR3 (Neurotrophic Tyrosine Kinase Receptor, type 3) or NT-3 Receptor, (GenBank Accession No. NM_002530), amino acids 456-825 (end) with N-terminal GST-tag, MW=68kDa, expressed in Sf9 cells via a Baculovirus expression system.

Aplicación

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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L Tessarollo et al.
Development (Cambridge, England), 118(2), 463-475 (1993-06-01)
The Trk family of tyrosine kinases encodes receptors for nerve growth factor-related neurotrophins. Here we present a developmental expression study of trkC, which encodes a receptor for neurotrophin-3 (NT-3). Like the related genes, trk and trkB, trkC is expressed primarily
L M McGregor et al.
Genomics, 22(2), 267-272 (1994-07-15)
TrkC is a receptor tyrosine kinase that is activated by neurotrophin-3, a factor important in the development of certain areas of the central nervous system. We have cloned and sequenced the human trkC cDNA and found that the predicted amino
F Lamballe et al.
Cell, 66(5), 967-979 (1991-09-06)
We report the isolation and molecular characterization of trkC, a new member of the trk family of tyrosine protein kinase genes. trkC is preferentially expressed in the brain. In situ hybridization studies revealed trkC transcripts in the hippocampus, cerebral cortex
Ke Zhang et al.
Stem cell reviews, 10(4), 612-625 (2014-05-03)
In the past decades, mesenchymal stem cells (MSCs) as a promising cell candidate have received the most attention in the treatment of spinal cord injury (SCI). However, due to the low survival rate and low neural differentiation rate, the grafted
Oswald Steward et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(42), 14013-14021 (2014-10-17)
We reported previously the formation of ectopic colonies in widespread areas of the nervous system after transplantation of fetal neural stem cells (NSCs) into spinal cord transection sites. Here, we characterize the incidence, distribution, and cellular composition of the colonies.
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