SML2220

SGC-AAK1-1N

≥98% (HPLC)

• Sinónimos: N-(6-(3-(Cyclopropanesulfonamido)phenyl)-1H-indazol-3-yl)isobutyramide, SGC-AAK1-1 Negative Control
• Fórmula empírica (notación de Hill): C₂₀H₂₂N₄O₃S
• Número de CAS: 2242913-80-8
• Peso molecular: 398.48
• Código UNSPSC: 51111800
• NACRES: NA.77

Propiedades

• Ensayo: ≥98% (HPLC)
• Formulario: powder
• color: white to beige
• solubilidad: DMSO: 2 mg/mL, clear
• temp. de almacenamiento: 2-8°C
• cadena SMILES: O=C(C(C)C)NC1=NNC2=C1C=CC(C3=CC(NS(C4CC4)(=O)=O)=CC=C3)=C2
• InChI: 1S/C20H22N4O3S/c1-12(2)20(25)21-19-17-9-6-14(11-18(17)22-23-19)13-4-3-5-15(10-13)24-28(26,27)16-7-8-16/h3-6,9-12,16,24H,7-8H2,1-2H3,(H2,21,22,23,25)
• Clave InChI: RAIAORGFMNXPOV-UHFFFAOYSA-N

Descripción

Acciones bioquímicas o fisiológicas

SGC-AAK1-1N is a structure analog of and the recommended negative control for SGC-AAK1-1 (AAK1 IC50 = 11 μM and 270 nM, respectively, by coupled enzyme assay; K_D = 8.8 μM/AAK1 & >10 μM/BIKE with SGC-AAK1-1N vs. K_D = 26 nM/AAK1 & 930 nM/BIKE with SGC-AAK1-1). For characterization details of the active probe, SGC-AAK1-1, please visit the SGC-AAK1-1 probe summary on the Structural Genomics Consortium (SGC) website.

SGC-AAK1-1, the active probe, is available from Sigma. To learn more about and purchase SGC-AAK1-1, click here.

To learn about other SGC chemical probes, visit sigma.com/sgc

Características y beneficios

SGC-AAK1-1N is a negative control for SGC-AAK1-1, a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable