SML0802

ZLN005

≥95% (HPLC)

• Sinónimos: 2-(4-tert-Butylphenyl)-1H-benzimidazole, 2-[4-(1,1-Dimethylethyl)phenyl]-1H-benzimidazole
• Fórmula empírica (notación de Hill): C₁₇H₁₈N₂
• Número de CAS: 49671-76-3
• Peso molecular: 250.34
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• Ensayo: ≥95% (HPLC)
• Formulario: powder
• color: white to beige
• solubilidad: DMSO: 10 mg/mL, clear
• temp. de almacenamiento: −20°C
• cadena SMILES: [nH]1c2c(nc1c3ccc(cc3)C(C)(C)C)cccc2
• InChI: 1S/C17H18N2/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3,(H,18,19)
• Clave InChI: LQUNNCQSFFKSSK-UHFFFAOYSA-N

Descripción

Acciones bioquímicas o fisiológicas

ZLN005 is a transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α). ZLN005 increased PGC-1 and downstream gene transcription in skeletal muscle, while reducing hepatic PGC-1α and gluconeogenesis genes. ZLN005 increased fat oxidation and improved the glucose tolerance, pyruvate tolerance, insulin sensitivity, hyperglycemia and dyslipidemia of diabetic db/db mice.

ZLN005 is a transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3