SMB01042

Allocryptopin

≥90% (LC/MS-ELSD)

• Sinónimos: β-Allocryptopine, γ-Homochelidonine, Fagarine I
• Fórmula empírica (notación de Hill): C₂₁H₂₃NO₅
• Número de CAS: 24240-04-8
• Peso molecular: 369.41
• Número MDL: MFCD00022318
• Código UNSPSC: 12352205
• NACRES: NA.25

Propiedades

• origen biológico: plant
• Ensayo: ≥90% (LC/MS-ELSD)
• Formulario: solid
• mol peso: 369.41
• solubilidad: water: slightly soluble
• aplicaciones: metabolomics; vitamins, nutraceuticals, and natural products
• temp. de almacenamiento: −20°C
• cadena SMILES: N1(CCc2c(cc4c(c2)OCO4)C(=O)Cc3c(c(c(cc3)OC)OC)C1)C
• InChI: 1S/C21H23NO5/c1-22-7-6-14-9-19-20(27-12-26-19)10-15(14)17(23)8-13-4-5-18(24-2)21(25-3)16(13)11-22/h4-5,9-10H,6-8,11-12H2,1-3H3
• Clave InChI: HYBRYAPKQCZIAE-UHFFFAOYSA-N

Descripción

Descripción general

Allocryptopin, an isoquinoline alkaliod, is a natural product commonly available from Allocryptopinus japonicus, Glaucium arabicum, Zanthoxylum beecheyanum, Berberis integerrima, and Macleaya cordata. This secondary metabolite derived from plant sources exhibits various biological activities such as anti-inflammatory, antiviral, and antitumor properties.

Aplicación

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Acciones bioquímicas o fisiológicas

Allocryptopine has been reported to possess strong antibacterial, anti-inflammatoty, antiparasitic, antineoplastic and anti-addictive activities. Allocryptopine inhibits human acetylcholinesterase and butyrylcholinesterase. It blocks hERG current in HEK293 cells. Allocryptopine strongly enhanced the I(peak) of the T353I channel by enhancing the plasma membrane (PM) expression of Nav1.5 and rescued defective trafficking after co-incubation with HEK293 cells that carry mutation channel 24 h.

Características y beneficios

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Otras notas

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Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable