SMB01024

Diuvaretin

≥90% (LC/MS-ELSD)

• Sinónimos: 1-[2,4-dihydroxy-3,5-bis[(2-hydroxyphenyl)methyl]-6-methoxyphenyl]-3-phenylpropan-1-one
• Fórmula empírica (notación de Hill): C₃₀H₂₈O₆
• Número de CAS: 61463-04-5
• Peso molecular: 484.54
• Número MDL: MFCD18975655
• Código UNSPSC: 12352205
• NACRES: NA.25

Propiedades

• origen biológico: plant
• Ensayo: ≥90% (LC/MS-ELSD)
• Formulario: solid
• mol peso: 484.54
• solubilidad: water: slightly soluble
• aplicaciones: metabolomics; vitamins, nutraceuticals, and natural products
• temp. de almacenamiento: −20°C
• InChI: 1S/C30H28O6/c1-36-30-23(18-21-12-6-8-14-25(21)32)28(34)22(17-20-11-5-7-13-24(20)31)29(35)27(30)26(33)16-15-19-9-3-2-4-10-19/h2-14,31-32,34-35H,15-18H2,1H3
• Clave InChI: KDEMELRYKGOXDL-UHFFFAOYSA-N

Descripción

Descripción general

Diuvaretin, a dihydrochalcone, is a natural product commonly available from Dipteryx odorata, Uvaria acuminata and Uvaria chamae plants. This plant metabolite exhibits various biological activities such as anti-inflammatory, antioxidant, antineoplastic, anti-angiogenic, and antimalarial properties.

Aplicación

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Acciones bioquímicas o fisiológicas

Diuvaretin exhibits cytotoxicity towards human promyelocytic leukemia HL-60 cells. It has a role as a metabolite, an antineoplastic agent and an antimalarial.

Diuvaretin inhibits NF-kB activation, hindering inflammation and cancer. It also suppresses tumor cell proliferation, induces apoptosis, and diminishes tumor growth and angiogenesis in mouse cancer models.

Características y beneficios

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Otras notas

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Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable