SAB5801055

Alpaca Anti-Rabbit IgG(Fcγ) single domain Antibody

recombinant Alpaca(VHH) Nano antibody

• Sinónimos: Recombinant Alpaca single variable domain secondary Nanobody
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: alpaca
• recombinante: expressed in E. coli
• conjugado: unconjugated (6*his tag and one cys were added at the C terminal of the VHH)
• forma del anticuerpo: affinity purified immunoglobulin
• tipo de anticuerpo: secondary antibodies
• clon: recombinant monoclonal
• formulario: lyophilized solid
• mol peso: 14 kDa
• reactividad de especies: Alpaca, rabbit
• técnicas: ELISA: 1:10000-1:50000; western blot: 1:10000-1:50000
• tamaño: 0.1 mL
• color: colorless
• isotipo: VHH
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C

Descripción

Descripción general

Alpaca Anti-Rabbit IgG(Fcγ) single domain Antibody is designed to specifically detect Fc region of rabbit IgG. It is a monovalent, single domain, recombinant antibody derived from the variable region of heavy chain of Alpaca pacous. Based on immunoelectrophoresis and/or ELISA, Alpaca Anti-Rabbit IgG(Fcγ) single domain Antibody reacts with the Fc region of rabbit IgG selectively but not with mouse, human, cynomolgus, rat, goat IgG.

Rabbit research antibodies are widely used in life science research. So far, four isotypes have been identified (IgA, IgE, IgG, and IgM) in rabbits. Each isotype has a different heavy chain. Rabbit has only one IgG subclass. The whole IgG molecule possesses both the Fc region and the Fab region, which possessing the epitope-recognition site. The IgG contains two heavy and light chains. The heavy chain is about 50 KD and the light chain is about 25 KD. The common IgG is monomeric with a molecular weight of approximately 150 kD.

VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(less than15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.

Especificidad

Fc region of Rabbit IgG
Isotype: VHH domain of alpaca IgG2b/2c

Inmunógeno

Recombinant Alpaca single variable domain secondary nano antibody

Envase

100 μg in Glass bottle

Forma física

Lyophilized from 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose

Reconstitución

Add 100uL dH2O or 100uL dH2O with 50% Glycerol to a final concentration of 1mg/mL

Almacenamiento y estabilidad

After reconstitution, store at –20 °C(Avoid freeze / thaw cycles). Stable for 12 months at -20°C

Otras notas

No cross-reactivity with mouse, human, cynomolgus, rat, goat IgG

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H317,H412
• Consejos de prudencia: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Clasificaciones de peligro: Aquatic Chronic 3 - Skin Sens. 1
• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable