SAB5702991

Anti-α/β-Synuclein (SNCA/SNCB) Antibody

rabbit monoclonal, 9E9X5

• Sinónimos: NACP, PARK1, PARK4, PD1
• Código UNSPSC: 12352203
• NACRES: NA.46

Propiedades

• Nombre del producto: Anti-alpha + beta Synuclein Antibody, clone 9E9X5, Rabbit Monoclonal,
• origen biológico: rabbit
• Nivel de calidad: 100
• Materiales: colorless
• clon: 9E9X5, monoclonal
• Formulario: liquid
• mol peso: 18 kDa
• reactividad de especies: human, rat, rat
• concentración: 1.35 mg/mL
• técnicas: immunofluorescence: 1:50 - 1:200; western blot: 1:500 - 1:2000
• color: colorless
• isotipo: IgG
• secuencia del inmunógeno: MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQL
• Nº de acceso UniProt: P37840; Q16143
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... SNCA(6620) , SNCB(6622)

Descripción

Descripción general

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]

Inmunógeno

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human alpha + beta Synuclein (P37840).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Aplicación

WB, IF/ICC

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1