SAB5701916

Anti-Phospho-Cdc6-S54 antibody produced in rabbit

• Código UNSPSC: 12352203
• NACRES: NA.43
• clon: monoclonal
• application: WB
• reactividad de especies: mouse, human
• técnicas: western blot: 1:500-1:2000

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• tipo de anticuerpo: primary antibodies
• clon: monoclonal
• Formulario: liquid
• reactividad de especies: mouse, human
• concentración: 0.33 mg/mL
• técnicas: western blot: 1:500-1:2000
• Nº de acceso UniProt: Q99741
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer52)
• Información sobre el gen: human ... CDC6(990)

Descripción

Descripción general

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]

Inmunógeno

A phospho specific peptide corresponding to residues surrounding S54 of human Cdc6

Forma física

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable