SAB5700422

Anti-Phospho-TNK2-Y284 antibody produced in rabbit

• Sinónimos: ACK, ACK-1, ACK1, TNK2, p21cdc42Hs
• Código UNSPSC: 12352203
• NACRES: NA.43
• clon: polyclonal
• application: WB
• reactividad de especies: human
• técnicas: western blot: 1:500-1:2000

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: 114; 119; 60
• reactividad de especies: human
• concentración: 1.71 mg/ml
• técnicas: western blot: 1:500-1:2000
• Nº de acceso UniProt: Q07912
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pTyr284)
• Información sobre el gen: human ... TNK2(10188)

Descripción

Descripción general

This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.

Inmunógeno

A synthetic phosphorylated peptide around Y284 of human TNK2 (NP_005772.3).

Forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Almacenamiento y estabilidad

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable