SAB5700342

Anti-Phospho-Camk2a-T286 antibody produced in rabbit

• Sinónimos: CAMK2A, CAMKA
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: 22; 54
• reactividad de especies: human, mouse, rat
• concentración: 0.8 mg/ml
• técnicas: western blot: 1:500-1:2000
• Nº de acceso UniProt: Q9UQM7
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pThr286)
• Información sobre el gen: human ... Camk2a(815)

Descripción

Descripción general

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Inmunógeno

A phospho specific peptide corresponding to residues surrounding T286 of human Camk2a

Forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Almacenamiento y estabilidad

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable