SAB5700330

Anti-Phospho-STAT1-S727 antibody produced in rabbit

• Sinónimos: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT1, STAT1 alpha, STAT91
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: 83; 87
• reactividad de especies: mouse, human, rat
• concentración: 1.31 mg/ml
• técnicas: immunohistochemistry: 1:50-1:100; immunoprecipitation (IP): 1:50-1:100; western blot: 1:500-1:2000
• Nº de acceso UniProt: P42224
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer727)
• Información sobre el gen: human ... STAT1(6772)

Descripción

Descripción general

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Inmunógeno

A synthetic phosphorylated peptide around S727 of human STAT1 (NP_009330.1).

Forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Almacenamiento y estabilidad

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable