SAB5700123

Anti-HuR/ELAVL1 antibody produced in rabbit

• Sinónimos: ELAV1, ELAVL1, HUR, HuR / ELAVL1, Hua, MelG
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: 36; 38
• reactividad de especies: human, rat, mouse
• concentración: 1.36 mg/ml
• técnicas: immunofluorescence: 1:50-1:200; immunohistochemistry: 1:100-1:200; western blot: 1:500-1:2000
• Nº de acceso UniProt: Q15717
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... ELAVL1(1994)

Descripción

Descripción general

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3′ untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.

Inmunógeno

Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human HuR / ELAVL1 (NP_001410.2).

Forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Almacenamiento y estabilidad

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable