SAB5600106

Anti-Phospho-AMPA Receptor antibody, GluR 1 subunit (Ser845), Rabbit Monoclonal

recombinant, expressed in HEK 293 cells, clone RM296, purified immunoglobulin

• Sinónimos: Glutamate Receptor 1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• recombinante: expressed in HEK 293 cells
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: RM296, monoclonal; recombinant monoclonal
• formulario: buffered aqueous glycerol solution
• reactividad de especies: human
• técnicas: immunohistochemistry: 1:100-1:200; western blot: 1:100-1:200
• isotipo: IgG
• Nº de acceso NCBI: 2890
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer845)
• Información sobre el gen: human ... GRIA1(2890)

Descripción

Descripción general

GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) is located on human chromosome 5q33.2. It is expressed mainly in brain areas.

Especificidad

This antibody reacts to human Glutamate Receptor 1, AMPA Receptor (GluR1) only when phosphorylated at Ser845. There is no cross-reactivity to GluR1 that is not phosphorylated at Ser845. This antibody may also react to mouse or rat Phospho-AMPA Receptor (GluR1) (Ser845) as predicted by immunogen homology.

Inmunógeno

A phospho-peptide corresponding to human Phospho-Glutamate Receptor 1 (GluR1) (Ser845).

Acciones bioquímicas o fisiológicas

GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) plays an important role in long-term potentiation (LTP). It is associated with migraine.

Características y beneficios

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Forma física

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable