SAB5600047

Anti-BRAF (V600E) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM8, purified immunoglobulin

• Sinónimos: Anti-B-RAF1, Anti-B-raf, Anti-BRAF-1, Anti-BRAF1, Anti-NS7, Anti-RAFB1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• recombinante: expressed in HEK 293 cells
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: RM8, monoclonal; recombinant monoclonal
• Formulario: buffered aqueous glycerol solution
• reactividad de especies: human
• concentración: ~1 mg/mL
• técnicas: ELISA: 0.5-2 μg/mL; immunoblotting: 0.5-2 μg/mL; immunocytochemistry: 0.5-5 μg/mL; immunohistochemistry: 0.5-5 μg/mL
• isotipo: IgG
• Nº de acceso NCBI: 673
• Nº de acceso UniProt: P15056
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... BRAF(673)

Descripción

Descripción general

BRAF (B-Raf proto-oncogene) is a serine-threonine kinase, that codes for B-Raf protein. It is located on human chromosome 7q34.

Especificidad

This antibody reacts to the BRAF V600E mutant. No cross reactivity with wild type BRAF.

Inmunógeno

Peptide corresponding to BRAF V600E mutant

Acciones bioquímicas o fisiológicas

BRAF (B-Raf proto-oncogene) participates in signaling direct cell growth. It induces tumor growth by initiating the mitogen-activated protein kinase (MAPK) pathway in various tumors like cutaneous melanoma and carcinomas of the thyroid and colon.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable