SAB5500139

Anti-MAGE-A1 antibody, Rabbit monoclonal

clone SP188, recombinant, expressed in proprietary host, affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• recombinante: expressed in proprietary host
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: SP188, monoclonal
• reactividad de especies: human (tested)
• técnicas: flow cytometry: 1:400; immunoblotting: 1:400; immunohistochemistry: 1:100
• isotipo: IgG
• Nº de acceso UniProt: P43355
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... MAGEA1(4100)

Descripción

Descripción general

Melanoma-associated antigen 1 (MAGE-A1) is a member of the MAGE family. It is encoded by the gene mapped to human chromosome Xq28.

Melanoma-associated antigen 1 (MAGE-A1) is one of the melanoma associated antigens (MAAs). MAGE-A1 is highly expressed in testis and some human solid tumors such as melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian and renal cell carcinomas.

Inmunógeno

Synthetic peptide derived from the C-terminus of human MAGE-A1 protein.

Acciones bioquímicas o fisiológicas

Members of MAGE family play a vital role in maintaining normal cellular physiology. Melanoma-associated antigen 1 (MAGE-A1) serves as a target antigen of patient-derived CD8⁺ T cells in melanoma. It might be potential target for treating melanoma patients.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable