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Merck
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Key Documents

SAB5200083

Sigma-Aldrich

Anti-SOD1 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

Sinónimos:

Anti-ALS1, Anti-Cu/Zn SOD, rat, Anti-IPOA, Anti-SOD1, Anti-SOD2, Anti-Superoxide dismutase1

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous glycerol solution

mol peso

antigen predicted mol wt 23 kDa

reactividad de especies

mouse, human, rat, bovine

concentración

1 mg/mL

técnicas

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: suitable

Nº de acceso NCBI

NP_058746.1

Nº de acceso UniProt

P00441

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

rat ... SOD1(24786)

Categorías relacionadas

Descripción general

Superoxide dismutase 1 (SOD1) acts as an anti-oxidant. The gene ID of the protein is 24786.

Especificidad

Detects a ~23 kDa (human) and 19 kDa (other species) proteins corresponding to the molecular mass of Cu/Zn superoxide dismutase (SOD) on SDS PAGE immunoblots.

Inmunógeno

Rat Cu/Zn SOD

Acciones bioquímicas o fisiológicas

Superoxide dismutase 1 (SOD1) offers protection to cells against reactive oxygen species.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

PBS, pH 7..0, 50% glycerol, 0.09% sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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What is the central question of this study? The current literature indicates that oxidative stress plays a major role in iron overload. Although exercise is a well-established approach to treat/prevent cardiovascular diseases, its effects on iron overload are not known.
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Free radical biology & medicine, 130, 174-188 (2018-10-14)
We previously demonstrated that the loss of female hormones induces cardiac and mitochondrial dysfunction in the female heart. Here, we show the impact of endurance training for twelve weeks, a nonpharmacological therapy against cardiovascular disease caused by ovariectomy and its
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Molecular mechanisms underlying neurodegenerative diseases converge at the interface of pathways impacting cellular stress, protein homeostasis and aging. Targeting the intrinsic capacities of neuroprotective proteins to restore neuronal function and/or attenuate degeneration represents a potential means toward therapeutic intervention. The
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Neurobiology of disease, 71, 317-324 (2014-08-20)
Approximately 20% of familial amyotrophic lateral sclerosis (FALS) cases are caused by mutant superoxide dismutase type 1 (mtSOD1). Although the mechanisms of mtSOD1-induced toxicity remain poorly understood, evidence suggests that accumulation of misfolded SOD1 is fundamental to its toxicity and
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