SAB4702104

Monoclonal Anti-CD271, purified produced in mouse

• Sinónimos: NGFR, TNFRSF16, p75NGFR, p75NTR
• Código UNSPSC: 12352203

Propiedades

• conjugado: unconjugated
• Nivel de calidad: 100
• tipo de anticuerpo: primary antibodies
• clon: NGFR5, monoclonal
• Formulario: buffered aqueous solution
• reactividad de especies: human, ( Non-human primates), ( Rabbit), ( Cat)
• concentración: 1 mg/ml
• técnicas: flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• isotipo: IgG1
• Nº de acceso UniProt: P08138
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... NGFR(4804)

Descripción

Descripción general

CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

Especificidad

The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.

Inmunógeno

Purified CD271 protein isolated from human melanoma cell line A875

Forma física

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Nota de preparación

Purified by protein-A affinity chromatography.

Almacenamiento y estabilidad

Store at 2-8°C. Do not freeze.

Otras notas

The antibody solution should be gently mixed before use.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable