SAB4700514

Monoclonal Anti-TCR beta antibody produced in mouse

clone MEM-262, purified immunoglobulin, buffered aqueous solution

• Sinónimos: Anti-TCR β (Vβ5.3-related)
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: MEM-262, monoclonal
• formulario: buffered aqueous solution
• reactividad de especies: human
• concentración: 1 mg/mL
• técnicas: flow cytometry: suitable
• isotipo: IgG2a
• Nº de acceso NCBI: NC_000007.13
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... TRB@(6957)

Descripción

Descripción general

The antibody MEM-262 recognizes β chains of the TCR expressed by HPB-ALL cell line [carrying V(beta5.3)] and a small subset of peripheral blood T cells.
TCR β/TCRB (T cell receptor β chain) is located on human chromosome 7q34. This gene has at least 65 rearrangeable Vβ gene segments (27 Vβ families), two Dβ segments (Dβ1 and Dβ2), two clusters of Jβ gene segments (Jβ1.1–Jβ 1.6 and Jβ2.1–Jβ2.7) and two Cβ gene segments.

Inmunógeno

Human thymoma cell line HPB-ALL

Aplicación

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2-8 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Acciones bioquímicas o fisiológicas

The complementary determining region 3 (CDR3) of the TCR β/TCRB (T cell receptor β) is essential for the identification of the major histocompatibility complex (MHC)−peptide complex.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable