SAB4700094

Monoclonal Anti-CD9-Biotin antibody produced in mouse

clone MEM-61, purified immunoglobulin, buffered aqueous solution

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• conjugado: biotin conjugate
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: MEM-61, monoclonal
• Formulario: buffered aqueous solution
• reactividad de especies: human
• concentración: 1 mg/mL
• técnicas: flow cytometry: suitable
• isotipo: IgG1
• Nº de acceso NCBI: NM_001769.3
• Nº de acceso UniProt: P21926
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CD9(928)

Descripción

Descripción general

Cluster of differentiation 9 (CD 9) molecule, a member of transmembrane 4 super family (TM4SF) or tetraspanin superfamily, possesses four transmembrane domain. In human chromosome, the gene CD9 is localized on 12p13.31. The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.

Inmunógeno

Pre-B cell line NALM-6

Aplicación

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1:400. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Acciones bioquímicas o fisiológicas

Functions of cluster of differentiation 9 (CD9) molecule (CD9) include cell proliferation, activation, motility, and metastasis of tumor cells. CD9 along with CD81 is implicated to play a key role in muscle cell fusion and myotube maintenance. CD9 is associated with Interleukin 16 (IL-16) and induces migration and activation of mast cells. CD9 is involved in megakaryopoiesis. CD9 is expressed in Cord Blood CD34+ cells and might play a key role in hematopoietic stem cell (HSC) homing. CD9 associates with β1 integrin, membrane type 1−matrix metalloproteinase (MT1-MMP) and CD26 for HSC motility and homing. CD9 is crucial for sperm-egg fusion during fertilization. CD9 is a key molecule for glycoprotein 130 (gp130) mediated tumorigenic signal transduction in glioblastoma and a potential target for therapy.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable