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Key Documents

SAB4700051

Sigma-Aldrich

Monoclonal Anti-CD3-PE antibody produced in mouse

clone APA1/1, purified immunoglobulin, buffered aqueous solution

Sinónimos:

Anti-CD3 (activation epitope)

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.44

origen biológico

mouse

conjugado

phycoerythrin (R-PE) conjugate

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

APA1/1, monoclonal

formulario

buffered aqueous solution

reactividad de especies

human, mouse

concentración

0.1 mg/mL

técnicas

flow cytometry: suitable

isotipo

IgG1

Nº de acceso NCBI

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... CD3(916)

Descripción general

The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.

Inmunógeno

Purified human CD3 proteins isolated from thymus

Aplicación

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

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