SAB4504665

Anti-phospho-BL-CAM (pTyr⁸⁰⁷) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 95 kDa
• reactividad de especies: mouse, rat, human
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:40000; western blot: 1:500-1:1000
• Nº de acceso NCBI: P20273
• Nº de acceso UniProt: P20273
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pTyr807)
• Información sobre el gen: human ... CD22(933)

Descripción

Descripción general

CD22 (cluster of differentiation 22) is a 140 kDa single-spanning membrane glycoprotein present on the surface of B cells. This gene belongs to the sialic acid-binding Ig-type lectin (Siglec) family. CD22 is mapped to human chromosome 19q13.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human BL-CAM around the phosphorylation site of Tyr807.

Immunogen Range: 776-825

Acciones bioquímicas o fisiológicas

CD22 (cluster of differentiation 22) helps to maintain B-cell homeostasis. This molecule act as an inhibitory coreceptor of the BCR (B cell receptor). CD22 is considered as a response regulator to control several aspects of B cell functions. Deficiency in CD22 or its pathways may contribute to autoimmunity.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable