SAB4504372

Anti-phospho-Cortactin (pTyr⁴²¹) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 61 kDa
• reactividad de especies: human, mouse, rat
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:20000; western blot: 1:500-1:1000
• Nº de acceso NCBI: Q14247
• Nº de acceso UniProt: Q14247
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pTyr421)
• Información sobre el gen: human ... CTTN(2017)

Descripción

Descripción general

Cortactin is an actin-related protein 2/3 (Arp2/3) complex–activating and filamentous (F)-actin–binding protein. This protein is coded by CTTN gene that maps to human chromosome 11q13.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human Cortactin around the phosphorylation site of Tyr421.

Immunogen Range: 388-437

Aplicación

Anti-phospho-Cortactin (pTyr421) antibody has been used in western blotting and immunoprecipitation.

Acciones bioquímicas o fisiológicas

Cortactin controls Arp2/3-mediated actin polymerization. This protein also modulates aggressive cancer cell traits like tumor growth, cancer cell invasion and motility, and serum- and anchorage-independent growth.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable