SAB4504269

Anti-phospho-TGF β Receptor II (pSer^225/250) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.43

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 64 kDa
• reactividad de especies: mouse, rat, human
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:10000; immunohistochemistry: 1:50-1:100
• Nº de acceso NCBI: P37173
• Nº de acceso UniProt: P37173
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer225/pSer250)
• Información sobre el gen: human ... TGFBR2(7048)

Descripción

Descripción general

Transforming growth factor β receptor 2 (TGFBR2) is a serine/threonine protein kinase, that belongs to the TGFβ receptor subfamily. It is located on human chromosome 3p24.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human TGF beta Receptor II around the phosphorylation site of Ser225/250.

Immunogen Range: 191-240

Acciones bioquímicas o fisiológicas

Transforming growth factor β receptor 2 (TGFBR2) plays an important role in signal transduction resulting in mitogenic responses. Mutation in TGFBR2 result in Loeys-Dietz syndrome and Marfan syndrome.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable